• Hippocampus-Avoidance Whole-Brain Radiation Therapy Is Efficient in the Long-Term Preservation of Hippocampal Volume 

      Popp, Ilinca; Rau, Alexander; Kellner, Elias; Reisert, Marco; Fennell, Jamina; Rothe, Thomas; Nieder, Carsten; Urbach, Horst; Egger, Karl; Grosu, Anca L.; Kaller, Christoph P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-19)
      Background and Purpose: With improved life expectancy, preventing neurocognitive decline after cerebral radiotherapy is gaining more importance. Hippocampal damage has been considered the main culprit for cognitive deficits following conventional whole-brain radiation therapy (WBRT). Here, we aimed to determine to which extent hippocampus-avoidance WBRT (HA-WBRT) can prevent hippocampal atrophy ...
    • Local control and possibility of tailored salvage after hypofractionated stereotactic radiotherapy of the cavity after brain metastases resection 

      Bilger, Angelika; Bretzinger, Eva; Fennell, Jamina; Nieder, Carsten; Lorenz, Hannah; Oehlke, Oliver; Grosu, Anca-Ligia; Specht, Hanno M.; Combs, Stephanie E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-09)
      In patients undergoing surgical resection of brain metastases, the risk of local recurrence remains high. Adjuvant whole brain radiation therapy (WBRT) can reduce the risk of local relapse but fails to improve overall survival. At two tertiary care centers in Germany, a retrospective study was performed to evaluate the role of hypofractionated stereotactic radiotherapy (HFSRT) in patients with brain ...